Detailed Adsense Information
Placing AdSense ads prominently on the top of the content
You should do this if you are providing a free tool which gives exceptional (perceived) value to its users. Also sites which are known market leaders with a huge following can do well this way.
Placing AdSense ads at the bottom of the content
Allows you to sell the information that
will sell the click.
Is a good idea if you are in an industry which requires trust.
Placing AdSense in an inline block
If you are a bs website trying to eat cake
from Google this may fit well in the dead center of your
pages.
If you are primarily an article website this may be the
way to integrate it into the content.
Blending AdSense in the page content
Probably the most effective way to serve
ads if you can blend it properly.
Works well in directory styled web sites.